Mesothelioma - Overview of Malignant Mesothelioma Cancer

 Abstract Epidermoid cysts are histologically benign, slow-growing congenital neoplasms of the central nervous system that may arise from retained ectodermal implants. The epidermoid lesions are generally caused during the 3 rd to 5 th week of gestation by an incomplete cleavage of the neural tissue from the cutaneous ectoderm, though it can also happen later in life due to introduction of skin elements by skin puncture, trauma or surgery. We present this unique case of a petromastoid epidermoid cyst associated with ipsilateral cerebellar abscesses, presenting 20 years after a penetrating trauma to the external auditory canal. Radical excision of both lesions and revision of the previous fistulous tract was performed. We present the diagnostic challenge and the operative treatment of this unique case, which to our knowledge is the first where an epidermoid cyst and an adjacent brain abscess occurred as a result of a single traumatic event. Keywords: Epidermoid cyst, penetrat...

Background: Epidermoid cysts, one of the common benign intradermal or subcutaneous tumors commonly result from the trauma to the pilosebaceous unit in the hair bearing area. In areas without hair, these cysts are considered implantation and proliferation of squamous epithelium into the dermis due to injury. Aims: The aim is to evaluate the clinicopathological details with emphasis on unusual findings related to epidermoid cysts. Study Design: This is a retrospective cross-sectional study carried out over 2 years. Materials and Methods: A total of 103 cases of epidermoid cysts were included in the study. The clinical details such as age, gender, sites, and dimensions were noted. The histopathological findings were evaluated and correlated with the clinical findings. Results: The highest incidence was observed in the age group of 21–30 years (23.3%, 24/103) and the most common affected region was the head and neck region (32%, 33/103). The size of cysts ranged from 0.3 to 9 cm in diam...

1Department of Imaging & Interventional Radiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong 2Department of Radiology, Kwong Wah Hospital, Kowloon, Hong Kong 3Department of Anatomical & Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong Received 12 August 2014; Accepted 26 December 2014 Academic Editor: Yoshito Tsushima Copyright © 2015 Eric K. C. Law et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Epidermoid cysts are benign slow growing extra-axial tumours that insinuate between brain structures, while their occurrences in intra-axial or intradiploic locations are exceptionally rare. We present the clinical, imaging, and pathological findings in two patients with atypical epidermoid cysts. CT and ...

An internal abdominal herniation is the extension of an abdominal organ through a mesenteric or peritoneal aperture. These rare lesions can be congenital or acquired as a result of trauma or intra-abdominal surgery. There is an association of this lesion with intestinal malrotation. Internal abdominal herniations rarely present during childhood, even when the underlying cause is developmental. The clinical manifestations of internal abdominal herniation are nearly always nonspecific. Patients may report abdominal pain or discomfort that tends to be episodic. The pain is most often localized to the periumbilical region. Nausea may occur. Manifestations of an acute bowel obstruction develop if there is bowel incarceration. CT is the most useful diagnostic imaging study for the evaluation of internal abdominal herniations; contrast studies of the bowel and standard radiographs serve roles as well.1,2 Six types of intra-abdominal herniations are generally recognized: paraduodenal hernia...

Patterns of immediate breast reconstruction in New South Wales, Australia: a population‐based study Yingyu Feng Kathy Flitcroft Marina T. van Leeuwen Adam G. Elshaug Andrew Spillane Sallie‐Anne Pearson ANZ Journal of SurgeryFirst Published:  16 August 2019 This study is the most comprehensive Australian analysis of immediate breast reconstruction (IBR) utilisation patterns through a population‐based study. It revealed that wide inter‐hospital variation exists in IBR rates within NSW, which raises concerns about potential inequities in access to IBR services and unmet demand in certain areas of NSW. Explaining the underlying drivers for IBR variation is the first step in identifying policy solutions to redress the issue. AbstractFull textPDFReferencesRequest permissions Surgical aortic valve replacement in Australia, 2002–2015: temporal changes in clinical practice, patient profiles and outcomes Si Si Graham S. Hillis Frank M. Sanfilippo Julian Smith Lavinia Tran Christopher...

Abstract Cystic lesions deriving from the omentum are rare benign clinical conditions of uncertain etiopathogenesis. In this report we describe a case of antenatal diagnosed intra‐abdominal cystic mass, which, due to the absence of symptomatology and constant ultrasound morphology over time, did not require immediate treatment. The present patient was followed up until surgery, which was performed at 4 years of age: on laparoscopy a cyst within the greater omentum was identified and excised. Histopathology indicated a cyst with epidermoid structure, which is unusual among the omental cysts reported in the literature.

Case Report Development of metachronous rectal cancers in a young man with dyskeratosis congenita: a case report DKC1 (dyskerin pseudouridine synthase 1) is a causative gene for X-linked dyskeratosis congenita. Approximately 8% of patients with dyskeratosis congenita have malignancy, but information about the development of... Authors: Motoko Watanabe, Gou Yamamoto, Kenji Fujiyoshi, Yoshito Akagi, Miho Kakuta, Yoji Nishimura and Kiwamu Akagi Citation:Journal of Medical Case Reports 2019 13:117 Published on: 27 April 2019 View Full Text View PDF Content Type: Case Report Successful total en bloc spondylectomy of the L3 vertebra with a paravertebral giant cell tumor following preoperative treatment with denosumab: a case report Giant cell tumor is known to be a benign neoplasm that arises most commonly in the long bones, while cases in the spine are rare. Recently, denosumab, a monoclonal antibody that inhibits receptor activator of ... Authors: Hideyuki Kinoshita, Su...

Infarcted Adenomatoid Tumour of Epididymis: A Rare Case Report A. Gupta,1 M. Livingston,1 R. Singh,1 D. Tansey,1,2 and L. Solomon1 1Urology Department, Queen Alexandra Hospital, Southwick Road, Cosham, Portsmouth PO6 3LY, UK 2Histopathology Department, Queen Alexandra Hospital, Southwick Road, Cosham, Portsmouth PO6 3LY, UK Received 18 January 2013; Accepted 18 March 2013 Academic Editors: F. Bruyere, K.-S. Lee, G. Lombardi, and J. Palou-Redorta Copyright © 2013 A. Gupta et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Paratesticular tumours are pathologically rare. The vast majority are benign in nature with adenomatoid tumours representing the most common pathological entity. We present the case of a 32-year-old man, from the Indian subcontinent, who presented with a painful scrotal swelling ...

INTRODUCTION The splenic lesions that have cystic presentation include a range of disorders. We discuss these non-parasitic ones, which are: the primary or true cysts (epithelial, epidermoid), pseudocysts (serous or hemorrhagic), vascular cysts (post-infarction, peliosis) and cystic neoplasms (hemangioma, lymphangioma, lymphoma and metastases). Splenic cysts are more frequent in the second and third decades of life, but they may appear in other age groups1,2. In 1829, Andral was responsible for the first description of a non-parasitic cyst of the spleen3. Robbins (1978) reviewed a series of 42,327 autopsies over 25 years, founding 32 patients with splenic cysts. Subsequently, isolated cases have been reported and, in 1978, approximately 600 cases were confirmed in the literature4,5. Splenic anatomy and physiology The splenic size and configuration vary. Typical parameters include dimensions of 12 x 7 x 4 cm and a weight of 150 grams (range 100-200 grams) and an anatomic rela...

Selected other problematic testicular and paratesticular lesions: rete testis neoplasms and pseudotumors, mesothelial lesions and secondary tumors Mahul B Amin Departments of Pathology, Urology, Hematology and Oncology, Emory University School of Medicine, Atlanta, GA, USA The proximity and, in some instances, communication between several structures in the testis and paratestis (rete testis, epididymis, mesothelium, vestigial epithelium and paratesticular soft tissue) result in a plethora of interesting tumors and tumor-like lesions that together pose a formidable diagnostic challenge both because of their morphologic overlap and rarity. The occasional spread of tumors primarily at other sites to this region adds to the potential problem encountered. This review provides an overview of the pathology of nonmesenchymal paratesticular neoplasms and pseudotumors with a focus on the approach to tubulopapillary neoplasms for which diagnostic considerations may include carcinom...

Journal of Indian Association of Pediatric Surgeons, Vol. 15, No. 2, April-June, 2010, pp. 70-71 Case Report Infarction of a polyp within a mesenteric cyst: An unusual presentation as an acute abdomen Sonia Gon1, Bipasa Majumdar1, Aditi Bhattacharyya1, Tushar K Das1, Indranil Chatterjee2 1 Department of Pathology, R G Kar Medical College & Hospital, Kolkata, India 2 Department of Pediatric Surgery, R G Kar Medical College & Hospital, Kolkata, India Correspondence Address: Sonia Gon Flat 1B, 23 Park Side Road, Kolkata - 700 026 India drmarur@yahoo.com PMID: 20975788 DOI: 10.4103/0971-9261.70647 Abstract A case of mesenteric cyst in a five-year-old male child who presented with acute abdomen due to an infarcted polyp present within the cyst is reported. To the best of our knowledge, such an event has never been reported in the literature previously. Keywords: Acute abdomen, infarcted polyp, mesenteric cyst Introduction Mesenteric cysts are rare, intr...

Abstract Primary splenic cyst is a relatively rare entity; they comprise only about 10% of benign non-parasitic cysts. Most of these are asymptomatic and are observed incidentally during abdominal ultrasonography. The number of diagnosed splenic cyst cases seems to have risen because of the increasing use of abdominal imaging techniques. However, definite diagnosis is possible only after splenectomy when epithelial lining is confirmed histologically. We report a case of a 14-year-old child who presented with fullness of abdomen and pain in the left hypochondrium since last few months. First impression made was in favor of a splenic lymphangioma of size 8 × 8 cm which was based on a Computerized tomography scan and the sonographic findings. Splenectomy was performed and was sent for histopathological examination which in combination with immunohistochemistry revealed findings suggestive of primary epithelial cyst. A large cystic mass with a relatively thin wall localized in the spl...

   Abstract Splenic cysts are uncommon lesions and are classified as true or pseudocysts based on the presence of an epithelial lining. True congenital cysts can be epidermoid, dermoid or endodermoid and require surgery when large, sympthomatic or complicated. Ultrasonography and computerised tomography scan are useful for diagnosis and serum test for echinococcosis should be done. Several procedures, open or laparoscopic, have been described, with emphasis on the spleen-preserving surgery, when possible. We present a boy with a giant symptomatic epidermoid cyst in whom total splenectomy by open technique was carried out. Keywords: Children, epidermoid cyst, management, splenic cyst    Introduction Top Splenic cysts are unusual in everyday surgical practice, especially in western countries and less than 1000 cases have been described in the literature. [1] They are classified as true (primary, 25%) lined by epithelium or false cysts (pseudocysts or seco...